SUBHEAD: Test result is strongest demonstration so far of altered growth and development in offspring of GE-fed mothers.
By Jonathan Latham PhD on 29 October 2015 in AlterNet -
(http://www.alternet.org/personal-health/genetically-engineered-soybeans-give-altered-milk-and-stunted-offspring-researchers)
Image above: Goats eating soybean feed. From (https://www.flickr.com/photos/baalands/19335878734).
Pregnant goats fed with genetically engineered (GE) soybeans have offspring who grow more slowly and are shorter, according to a new Italian study (Tudisco et al., 2015). Publishing in the journal of Small Ruminant Research, the researchers were testing the results of supplementing the feed of female goats with Roundup Ready GE soybeans.
Roundup Ready soybeans are engineered to resist the herbicide Roundup and are sold by agribusiness giant Monsanto. They are some of the most widely grown soybeans in the world.
The reduced growth of the goat kids was attributed by the researchers to their observation that the milk of the GE-fed mothers was significantly less nutritious and contained less of the IgG antibodies important for early growth.
“This was a carefully conducted study” commented Dr Judy Carman, Director of the Institute of Health and Environmental Research, Australia. She was not involved in the research, but told Independent Science News that:
After the mothers gave birth all offspring were fed only with their mother’s milk for sixty days. The growth of these kids was measured twice. After both thirty days and sixty days the kids of GE-fed mothers were approximately 20% lower in weight and shorter in stature. Both these differences were statistically significant.
Lower offspring weights were not the only unexpected findings. The researchers also found that the milk of GE-fed goats was lower in protein and fat. This difference in milk quality was large (6% protein in both GE-fed groups versus 18% in both non-GE fed groups) for the first few weeks after birth but gradually disappeared—even though the mothers continued to be fed the GE soybeans.
Additionally, the researchers also found that the colostrum produced by GE-fed mothers had low amounts of IgG antibodies. These antibodies are important for growth and for healthy immune development.
A third difference noted by the researchers was that transgenic DNA could be detected in the colostrum of most (10/16) of the GE-fed goats. No transgene DNA was detected in the milk of goats fed non-GE soybeans. This is not the first time that transgene DNA (or non-transgenic DNA) has been found in the milk of ruminants, however.
Interestingly, the researchers found that all of the kids were of similar size at birth, regardless of whether their mothers ate Roundup Ready GE soybeans or not. The researchers therefore proposed that the stunting of the offspring of GE-fed mothers reflected a milk deficiency. Presumably either the lower nutritional value of the colostrum and milk of GE-fed mothers or the colostrum antibody differences that were observed.
The authors noted that low IgG antibody levels in colostrum are correlated in other ruminants with slower growth and also that IgG antibodies are known to have a role in nutrient absorption because they promote gut development in newborns.
The researchers did not discuss whether the transgene DNA fragments found in the milk played a role in altering kid development.
This result is the strongest demonstration so far of altered growth and development in offspring of GE-fed mothers. The same researchers in 2010 showed altered activity of the lactic dehydrogenase enzyme in kids fed milk from mothers that ate GE Roundup Ready soybeans. In that previous study however, no additional effects on goat offspring were detected (Tudisco et al., 2010).
“It is already known that Roundup Ready soybeans have various defects including a Manganese deficiency. Yet regulators and GMO developers have continuously dismissed credible reports of GMO crops causing apparent harm to animals, from many different research groups,” said Dr Allison Wilson of The Bioscience Resource Project. “Hopefully they will not ignore yet another study.”
.
By Jonathan Latham PhD on 29 October 2015 in AlterNet -
(http://www.alternet.org/personal-health/genetically-engineered-soybeans-give-altered-milk-and-stunted-offspring-researchers)
Image above: Goats eating soybean feed. From (https://www.flickr.com/photos/baalands/19335878734).
Pregnant goats fed with genetically engineered (GE) soybeans have offspring who grow more slowly and are shorter, according to a new Italian study (Tudisco et al., 2015). Publishing in the journal of Small Ruminant Research, the researchers were testing the results of supplementing the feed of female goats with Roundup Ready GE soybeans.
Roundup Ready soybeans are engineered to resist the herbicide Roundup and are sold by agribusiness giant Monsanto. They are some of the most widely grown soybeans in the world.
The reduced growth of the goat kids was attributed by the researchers to their observation that the milk of the GE-fed mothers was significantly less nutritious and contained less of the IgG antibodies important for early growth.
“This was a carefully conducted study” commented Dr Judy Carman, Director of the Institute of Health and Environmental Research, Australia. She was not involved in the research, but told Independent Science News that:
“The differences in the composition of the colostrum between the mothers fed the GE soy and the non-GE soy were particularly striking. The colostrum from the GE-fed mothers contained only 2/3 of the fat, 1/3 of the protein and close to half of the IgG of the mothers fed the non-GM soy.”To carry out these experiments the researchers divided pregnant female Cilentana goats into four groups, sixty days before kidding. Two of the groups were fed goat food containing GE Roundup Ready soybeans (at two different concentrations). The other two groups were fed conventional (non-GE) soybeans, also at two different concentrations.
After the mothers gave birth all offspring were fed only with their mother’s milk for sixty days. The growth of these kids was measured twice. After both thirty days and sixty days the kids of GE-fed mothers were approximately 20% lower in weight and shorter in stature. Both these differences were statistically significant.
Lower offspring weights were not the only unexpected findings. The researchers also found that the milk of GE-fed goats was lower in protein and fat. This difference in milk quality was large (6% protein in both GE-fed groups versus 18% in both non-GE fed groups) for the first few weeks after birth but gradually disappeared—even though the mothers continued to be fed the GE soybeans.
Additionally, the researchers also found that the colostrum produced by GE-fed mothers had low amounts of IgG antibodies. These antibodies are important for growth and for healthy immune development.
A third difference noted by the researchers was that transgenic DNA could be detected in the colostrum of most (10/16) of the GE-fed goats. No transgene DNA was detected in the milk of goats fed non-GE soybeans. This is not the first time that transgene DNA (or non-transgenic DNA) has been found in the milk of ruminants, however.
Interestingly, the researchers found that all of the kids were of similar size at birth, regardless of whether their mothers ate Roundup Ready GE soybeans or not. The researchers therefore proposed that the stunting of the offspring of GE-fed mothers reflected a milk deficiency. Presumably either the lower nutritional value of the colostrum and milk of GE-fed mothers or the colostrum antibody differences that were observed.
The authors noted that low IgG antibody levels in colostrum are correlated in other ruminants with slower growth and also that IgG antibodies are known to have a role in nutrient absorption because they promote gut development in newborns.
The researchers did not discuss whether the transgene DNA fragments found in the milk played a role in altering kid development.
This result is the strongest demonstration so far of altered growth and development in offspring of GE-fed mothers. The same researchers in 2010 showed altered activity of the lactic dehydrogenase enzyme in kids fed milk from mothers that ate GE Roundup Ready soybeans. In that previous study however, no additional effects on goat offspring were detected (Tudisco et al., 2010).
“It is already known that Roundup Ready soybeans have various defects including a Manganese deficiency. Yet regulators and GMO developers have continuously dismissed credible reports of GMO crops causing apparent harm to animals, from many different research groups,” said Dr Allison Wilson of The Bioscience Resource Project. “Hopefully they will not ignore yet another study.”
.
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